We are here with our UEFA Champions League Predictions this week for matchday 2. The UEFA Champions League returns this week with Matchday 2 promising plenty of goals, thrilling encounters and potential upsets across Europe. Several heavyweight clubs will be looking to strengthen their positions, while others face difficult challenges away from home.
Manchester City vs Paris Saint-Germain headlines Wednesday's action, while Atlético Madrid vs Manchester United and Roma vs Real Madrid are among Tuesday and Wednesday's other standout fixtures.
Here are our Champions League predictions for all 18 Matchday 2 games, including predicted scores and key talking points.
Tuesday, October 13, 2026: Champions League Predictions
1. Lens vs Sporting CP
Sporting CP are expected to secure a comfortable away victory against Lens. The Portuguese side will look to control possession and exploit opportunities in the final third, making them favourites to collect all three points.
Prediction: Lens 0 - 2 Sporting CP
2. Sabah vs Slavia Prague
Sabah could suffer another disappointing result following their defeat against Manchester United last gameweek. Slavia Prague will look to capitalise on their opponents' weaknesses and secure a convincing victory on the road.
Prediction: Sabah 0 - 2 Slavia Prague
3. Arsenal vs Lille
Mikel Arteta's Arsenal are expected to dominate Lille at the Emirates Stadium. The Gunners possess the attacking quality to overwhelm the visitors and could produce a commanding performance in front of their supporters.
Prediction: Arsenal 4 - 1 Lille
4. Atlético Madrid vs Manchester United
Atlético Madrid could inflict further damage on Michael Carrick's Manchester United reign after the recent draw against Tottenham. Diego Simeone's side will aim to exploit United's defensive vulnerabilities and claim an important European victory.
Prediction: Atlético Madrid 3 - 1 Manchester United
5. Inter Milan vs Club Brugge
Inter Milan are tipped to emerge victorious in what promises to be an entertaining, high-scoring encounter. Club Brugge could create problems going forward, but Inter's attacking firepower should ultimately prove decisive.
Prediction: Inter Milan 4 - 2 Club Brugge
6. Galatasaray vs Barcelona
Goals could be plentiful when Barcelona travel to face Galatasaray in Istanbul. Lamine Yamal and Anthony Gordon are expected to shine in an exciting contest, with Barcelona possessing the quality to outscore their hosts.
Prediction: Galatasaray 2 - 5 Barcelona
7. RB Leipzig vs PSV Eindhoven
RB Leipzig could secure a narrow victory against PSV Eindhoven in a closely contested encounter. Home advantage might prove crucial, although PSV are capable of making life difficult for the German side.
Prediction: RB Leipzig 2 - 1 PSV Eindhoven
8. Viking FK vs Bayern Munich
Bayern Munich are expected to produce one of the most dominant performances of Matchday 2. Harry Kane and Michael Olise could lead the charge as the German giants overwhelm Viking FK with their attacking quality.
Prediction: Viking FK 0 - 6 Bayern Munich
9. Villarreal vs Napoli
Villarreal and Napoli could deliver one of Tuesday's most entertaining matches. Both teams have the potential to cause damage in attack, but Napoli are tipped to edge a closely fought contest with a late decisive contribution.
Prediction: Villarreal 2 - 3 Napoli
Wednesday, October 14, 2026: Champions League Predictions
10. Feyenoord vs Como
Como are predicted to continue their impressive progress under Cesc Fàbregas with a comfortable away victory. Their tactical organisation and attacking quality could prove too much for Feyenoord.
Prediction: Feyenoord 0 - 3 Como
11. LASK vs Liverpool
Iraola's Liverpool are expected to enjoy a comfortable night against LASK. The English side should have enough quality to control the game, create numerous scoring opportunities and secure all three points.
Prediction: LASK 0 - 3 Liverpool
12. Roma vs Real Madrid
Roma could produce one of the biggest upsets of Matchday 2 by defeating Real Madrid. We expect Kylian Mbappé and Vinícius Júnior to struggle to make their usual impact, allowing Roma to capitalize and claim a memorable victory.
Prediction: Roma 2 - 1 Real Madrid
13. Aston Villa vs Fenerbahçe
Aston Villa are tipped to earn a convincing home victory against Fenerbahçe. Nicolas Jackson could be the standout performer as Villa exploit spaces in the visitors' defence and establish control early.
Prediction: Aston Villa 3 - 0 Fenerbahçe
14. Shakhtar Donetsk vs AEK Athens
Shakhtar Donetsk should have enough attacking quality to secure a relatively comfortable victory against AEK Athens. The Ukrainian side will look to take advantage of their opportunities and establish their superiority.
Prediction: Shakhtar Donetsk 3 - 1 AEK Athens
15. Bodø/Glimt vs Borussia Dortmund
Borussia Dortmund could be surprised by Bodø/Glimt in a challenging away fixture. The Norwegian side are capable of making life uncomfortable for their opponents, and we expect both teams to settle for a share of the points.
Prediction: Bodø/Glimt 2 - 2 Borussia Dortmund
16. Manchester City vs Paris Saint-Germain
The standout fixture of the week could produce a spectacular contest between two European heavyweights. Pep Guardiola is expected to attend in support of Manchester City amid the club's ongoing financial fair play controversy. However, PSG are tipped to outscore Erling Haaland and his teammates in a thrilling encounter.
Prediction: Manchester City 2 - 4 Paris Saint-Germain
17. Real Betis vs Porto
Porto are expected to secure a narrow away victory against Real Betis. The Portuguese side could prove more clinical in the decisive moments, giving them the edge in what should be a competitive encounter.
Prediction: Real Betis 1 - 2 Porto
18. Slovan Bratislava vs Stuttgart
Stuttgart are backed to secure a comfortable victory against Slovan Bratislava. The German side should have the quality to control proceedings, create chances and leave with three valuable Champions League points.
Prediction: Slovan Bratislava 0 - 2 Stuttgart
Final Verdict: Our Champions League Matchday 2 Predictions
Bayern Munich's potential six-goal victory over Viking FK stands out as one of our boldest predictions, while Barcelona and PSG are also tipped to win high-scoring encounters. Meanwhile, Roma beating Real Madrid could be the biggest shock of the week.
With 18 fixtures scheduled across Tuesday and Wednesday, Matchday 2 promises plenty of drama, goals and intriguing storylines in the Champions League.