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Top 5 Best FPL Defenders This week: GW16, Premier League 2025-26

Here is our pick of the Best Fantasy Premier League defenders for this week (GW16), featuring top FPL options from clubs such as Arsenal, Chelsea, and Manchester United.

MF
Last updated: 12.12.2025
best fpl defenders gameweek 16 Premier League 2025-26

Welcome to our Gameweek 16 edition of best FPL Defenders for this week. Barring for 1 or 2 sides, the fixtures in GW16 are not the easiest for teams in the Premier League. Thus, there are very few FPL defender options for the week that could “absolutely” guarantee you great points. However, have no worries as we've done our expert research and come up with the best Fantasy Premier League defenders you can buy this week.  Let's not waste more time then, scroll down to find the best FPL defenders picks Gameweek 16.


Best Fantasy Premier League Defenders - Gameweek 16

Luke Shaw (Manchester United, £4.5m)

Ever since returning from a long injury lay-off, Luke Shaw has established himself as one of the favourites of Ruben Amorim in the Man United defense. The Englishman regularly starts for them at the moment, and is one of the best differential FPL defenders to pick this week. United are coming from a fantastic win over Wolves, and will be facing a Bournemouth side who have been quite underwhelming in recent games.


Marc Cucurella (Chelsea, £6.2m)

Chelsea's defense has been a bit shaky this season, but Marc Cucurella has been one of their better performers in defense. He also possesses a decent attacking threat as well, and thus has a great chance of scoring you much more than the usual clean sheet points. Chelsea will face Everton at home in GW16, and the home advantage might help them just win this game.


Jurrien Timber (Arsenal, £6.5m)

Gabriel is still a long way from coming back, and thus Gabriel stands out as not just the best Fantasy Premier League Arsenal defender pick for this week, but for the foreseeable future till the Brazilian is back from Injury. Arsenal face Wolves in Gameweek 16, and is one of those games where Timber could even end up scoring or assisting. An absolute must-visit for this week according to us.


Matty Cash (Aston Villa, £4.8m)

Matty Cash has been one of the best players for Aston Villa this season, and he's also been excellent from an FPL perspective as well. He's already scored 3 goals this season despite being a defender, and Aston Villa are also currently the best team in the league form wise. They'll be facing West Ham away this EPL weekend, who have been in mixed form since the appointment of Nuno Espírito Santo. At just  £4.8m, he's one of the best low-risk bargain FPL defenders for this week who could end up giving you solid returns.


Virgil Van Dijk (Liverpool, £6.0m)

One the most impressive aspects of Liverpool's win over Inter Milan in the Champions League was how fantastic they were defensively. This is especially good news for Liverpool defender owners in FPL considering how exposed the Liverpool defense has been in the Premier League. Keeping the game in Inter against mind, we see Virgil Van Dijk as one of the best FPL defenders for Gameweek 16. The Reds will be facing Brighton at home, and we could see the Dutchman repeat his heroics against Inter here.


These are our Best FPL defenders for this week (Gameweek 16). Choose your ideal Fantasy Premier League defenders from our list according to your available budget and long-term transfer plans. That's it from our side, see you soon with our best Fantasy Premier League defenders list for Gameweek 17.

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